We use ProStride to reduce pain associated with arthritis and slow the degrading of cartilage while improving mobility.Īnother osteoarthritis treatment we use is polyacrylamide hydrogel, which can stop the progression of the disease and reduce pain in arthritic joints.Īnother therapy commonly used is shockwave. PRP is used to treat soft tissue (tendon and ligament) injuries and promotes faster healing. IRAP is an anti-inflammatory treatment which prevents the interleukin-1 from binding to tissues such as joint cartilage, which causes inflammation. These tend to overlap in terms of how they work.Polyacrylamide gel (designed for joint lubrication).ProStride (a combination of PRP and IRAP).IRAP (Interleukin-1 Receptor Antagonist Protein).We typically use a combination of the following minimally invasive injection therapies since they complement each other in the healing process. The protein matrix contains native growth factors and anti-inflammatory proteins similar to PRP and IRAP but at much greater quantities. A significant difference is that the PulpCyte allograft contains stem cells which are imbedded in a protein matrix which protects the viability of the cells.
It is an allograft that is mechanically extracted without tissue processing such as non-marrow derived cells (cell culture) and fat-derived stem cells (fat tissue digestion), screened extensively for potential diseases and subsequently stored. PulpCyte®Ī product by VetGraft where we’ve seen remarkable results is called PulpCyte®. One of the advantages of the fat-derived product is that immune response in joints and soft tissues are much rarer compared to the bone marrow derived stem cell product. Adipose-derived stromal fraction is the more appropriate term used to describe this therapy. Fat-derived stem cells only contain 2-4% stem cells unless they are cultured and expanded. The stem cells can then be injected into the affected tendon, ligament or joint. The culture and expansion process takes approximately 3 weeks. The typical dose ranges from 10 to 25 million stem cells per treatment. Once the bone marrow has been obtained it is sent to a lab where it is cultured and expanded into millions of stem cells. In equine practice stem cells are commonly derived from bone marrow obtained from the sternum or the tuber coxae. This is the reason for the recent interest in storing umbilical cord blood in horses. The younger stem cells have an increased ability to heal and regenerate tissue compared to the adult stem cells. The younger or more immature the stem cell, the more potential they may have. These MSCs are found in bone marrow, fat, dental connective tissue, umbilical cord blood and tissue, and many other organs throughout the body. Using stem cells from different sources enables the horse to realize different benefits.Įquine regenerative medicine primarily uses mesenchymal stem cells (MSC), which reside in the bone marrow, as the premise in equine veterinary medicine is to primarily treat soft tissue and joint injuries. We inject stems cells directly into the injured or lesion area to help the horse’s body more effectively stimulate tissue healing. This equine therapy is an effective option for treatment for equine injuries and equine lameness. Stem cell therapy is now a very common regenerative therapy that may employ stem cells from various sources such as bone marrow and fat, dental connective tissue and amniotic fluid. Rich are pioneers in equine stem cell research and administration and there are thousands of success stories regarding the anti-inflammatory effects and accelerated healing provided by stem cell therapy. We are firm believers in minimalizing invasive treatment where applicable. With the development of new intravascular (especially intra-arterial) application techniques of stem cells, the treatment of laminitis and more inaccessible soft tissue injuries, such as those within the hoof, have become possible. The most common applications for Regenerative therapies in horses are currently soft tissue injuries (tendons and ligaments) and joints. These offer the possibility of successful treatment of previously life-threatening or career-ending injuries. The most common regenerative medicine currently includes stem cell, IRAP, and PRP therapies. Aristizabal have been involved in research studies and published in the equine and human literature on the biology and application of stem cells. Regenerative therapy is a specialty of Cave Creek Equine™ Sports Medicine & Surgery, as Dr.
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